Progestogens (also sometimes spelled progestagens or gestagens) are a class of steroid hormones that bind to and activate the progesterone receptor (PR). The most important progestogen in the body is progesterone (P4). Other endogenous progestogens include 17-hydroxyprogesterone, 5α-dihydroprogesterone, and 11-deoxycorticosterone. Synthetic progestogens are generally referred to as progestins. However, the terms progesterone, progestogen, and progestin are frequently used interchangeably both in the scientific literature and in clinical settings.
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